SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 5-5? SUBSTITUTED HYDANTOIN

Authors

  • S. V Kolhe

Keywords:

Synthesis, coumarone 3-one, mercuric acetate, urea, ethanolic 10% KOH,

Abstract

2 hydroxy substituted calcone (I a-d) was dissolved in DMSO and mercuric
acetate was added to it. The reaction mixture was refluxed for 3 hours and then diluted with
water. The solid separated was crystallized from rectified sprit to give coumarone 3-one i.e.
aurone (II a-d). Substituted aurone further refluxed with urea in ethanolic 10% KOH for 3
hours gives substituted hydantoin. The structural elucidation of compound was done on the
basis of analytical and spectral data

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Published

2018-05-30

Issue

Vol. 7 No. 6 (2018): May 2018

Section

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